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Fibre content of enteral feeds for the older child.

2009-09-13T17:36:00.001-07:00

J Hum Nutr Diet. 2009 Oct; 22(5): 414-21Evans S, Daly A, Davies P, Macdonald ABackground: There is currently a lack of clinical data on fibre requirements in UK children. Subsequently, the ideal fibre profile for enteral formulae designed to meet the requirements of older children is unknown. The present study aimed to investigate the effect of fibre supplementation on gastrointestinal function

Hepatic Segments and Vasculature: Projecting CT Anatomy onto Angiograms.

2009-09-12T15:58:00.001-07:00

Radiographics. 2009 Sep 4; Furuta T, Maeda E, Akai H, Hanaoka S, Yoshioka N, Akahane M, Watadani T, Ohtomo KHepatic transarterial interventional therapies such as chemoembolization and radiation embolization are important treatment options for hepatocellular carcinoma. Understanding the anatomy of individual arterial branches and hepatic segments is critical for selecting the correct

The role of survivin in the resistance of endometriotic stromal cells to drug-induced apoptosis.

2009-09-11T17:52:00.001-07:00

Hum Reprod. 2009 Sep 3; Watanabe A, Taniguchi F, Izawa M, Suou K, Uegaki T, Takai E, Terakawa N, Harada TBACKGROUND Decreased susceptibility of endometrial tissue to apoptosis may contribute to the pathogenesis of endometriosis. We investigate the role of survivin in the pathophysiology of endometriosis through the ability of ectopic and eutopic endometrial stromal cells (ESCs) to resist

Detection of pain-related molecules in the subchondral bone of osteoarthritic knees.

2009-09-10T23:35:00.000-07:00

Clin Rheumatol. 2009 Sep 3; Ogino S, Sasho T, Nakagawa K, Suzuki M, Yamaguchi S, Higashi M, Takahashi K, Moriya HKnee pain is predominant among osteoarthritis (OA) patients, but the mechanism is poorly understood. We investigated subchondral bone as a source of OA knee pain using immunohistochemistry. Fifteen medial-type OA knees with minimum involvement of the lateral compartment determined by

Completely Laparoscopic Subtotal Pancreatectomy with Splenic Artery Preservation.

2009-09-10T17:43:00.001-07:00

J Gastrointest Surg. 2009 Sep 2; Boutros C, Espat NJ, Somasundar PINTRODUCTION: Laparoscopic distal pancreatectomy has emerged as an attractive minimally invasive alternative for selected patients. Although technically challenging, distal pancreatectomy with splenic artery preservation has consistently been correlated with reduced blood loss and perioperative morbidity in multiple studies.

Incidental Pancreatic Cysts: A Frequent Finding in Liver-Transplanted Patients as Assessed by 3D T2-Weighted Turbo Spin Echo Magnetic Resonance Cholangiopancreatography.

2009-09-09T23:26:00.001-07:00

JOP. 2009; 10(5): 507-514Girometti R, Intini SG, Cereser L, Bazzocchi M, Como G, Del Pin M, Baccarani U, Toniutto P, Zuiani CCONTEXT: The increasing frequency of incidental pancreatic cysts at imaging is a challenging topic due to the uncertainty of the aggressiveness of these lesions, especially small ones. To date, no data exist about their prevalence in a population of liver-transplanted

Clinical phenotype of cystic fibrosis patients with the G551D mutation.

2009-09-09T02:40:00.001-07:00

QJM. 2009 Sep 4; Comer DM, Ennis M, McDowell C, Beattie D, Rendall J, Hall V, Elborn JSBACKGROUND: Data on whether the phenotype of cystic fibrosis (CF) patients with compound heterozygocity for G551D (Gly551Asp) differs from patients with F508del (Phe508del) homozygous mutations is divergent. AIM: We hypothesized that CF patients with the G551D mutation would have less severe disease than

Shielding, a new pathogen defense mechanism against polymorphonuclear neutrophilic leukocytes (PMNs).

2009-09-08T17:28:00.000-07:00

Microbiology. 2009 Sep 3; Cornelis PIn an article published in this issue, Alhede et al. demonstrate that the opportunistic pathogen Pseudomonas aeruginosa can react to the presence of PMNs by producing abundant quantities of rhamnose-containing glycolipid biosurfactants, the rhamnolipids. PMNs are phagocytic cells and are important players in the innate immune response since they produce a

Prevalence of intestinal parasites in pet dogs in the United States.

2009-09-05T16:28:00.000-07:00

Vet Parasitol. 2009 Aug 5; Little SE, Johnson EM, Lewis D, Jaklitsch RP, Payton ME, Blagburn BL, Bowman DD, Moroff S, Tams T, Rich L, Aucoin DTo determine the national, regional, and age-related prevalence of intestinal parasites in dogs presenting to veterinarians in the United States, we reviewed the results of examination via zinc sulfate centrifugal flotation of 1,199,293 canine fecal

Expanding the spectrum of malignant progression in solitary fibrous tumors: a study of 8 cases with a discrete anaplastic component--is this dedifferentiated SFT?

2009-09-02T08:07:00.001-07:00

Am J Surg Pathol. 2009 Sep; 33(9): 1314-21Mosquera JM, Fletcher CDDedifferentiation is a well recognized, if sometimes controversial, form of tumor progression in certain types of soft tissue and bone sarcoma, and confers a worse prognosis when compared with the low-grade counterpart. To date, dedifferentiation has not been described in solitary fibrous tumor (SFT). Among 948 cases of both

Lack of CFTR in Skeletal Muscle Predisposes to Muscle Wasting and Diaphragm Muscle Pump Failure in Cystic Fibrosis Mice.

2009-08-31T18:42:00.001-07:00

PLoS Genet. 2009 Jul; 5(7): e1000586Divangahi M, Balghi H, Danialou G, Comtois AS, Demoule A, Ernest S, Haston C, Robert R, Hanrahan JW, Radzioch D, Petrof BJCystic fibrosis (CF) patients often have reduced mass and strength of skeletal muscles, including the diaphragm, the primary muscle of respiration. Here we show that lack of the CF transmembrane conductance regulator (CFTR) plays an

Azithromycin and clarithromycin inhibit lipopolysaccharide-induced murine pulmonary neutrophilia mainly through effects on macrophage-derived GM-CSF and IL-1{beta}

2009-08-30T15:51:00.001-07:00

J Pharmacol Exp Ther. 2009 Jul 24; Bosnar M, Bosnjak B, Euziae S, Hrvaeiae B, Marjanoviae N, Glojnariae I, Euliae O, Parnham MJ, Erakoviae Haber VMacrolide antibiotics possess immunomodulatory / anti-inflammatory properties. These properties are considered fundamental for the efficacy of macrolide antibiotics in the treatment of chronic inflammatory diseases like diffuse panbronchiolitis and

Improving genetic health care: A Northern New England pilot project addressing the genetic evaluation of the child with developmental delays or intellectual disability.

2009-08-30T08:09:00.001-07:00

Am J Med Genet C Semin Med Genet. 2009 Jul 20; Moeschler JB, Amato RS, Brewster T, Burke L, Dinulos MB, Smith R, Smith W, Miller PIn 2006, all clinical genetics practices in Northern New England (Vermont, New Hampshire, and Maine) formed a learning collaborative with the purpose of improving genetic health care and outcomes. This article describes the current status of this effort. The

Morphological and molecular phylogenetic analysis of two Saprolegnia sp. (Oomycetes) isolated from silver crucian carp and zebra fish.

2009-08-30T03:52:00.001-07:00

Mycol Res. 2009 Feb 6; Ke XL, Wang JG, Gu ZM, Li M, Gong XNTwo Saprolegnia isolates, JY isolated from silver crucian carp (Carassius auratus gibelio Bloch) and BMY isolated from zebra fish (Brachydanio rerio Hamilton) came from infections occurring concurrently in different locations in China. To confirm whether the two isolates were from the same Saprolegnia clone, comparative studies have been

Noncontact in vivo scanning laser microscopy of filtering blebs.

2009-08-28T22:17:00.001-07:00

J Glaucoma. 2009 Aug; 18(6): 479-83Sbeity Z, Palmiero PM, Tello C, Liebmann JM, Ritch RPURPOSE: To evaluate the ability of a noncontact, prototype scanning laser confocal microscope to image microstructural features of filtering blebs in vivo and to correlate these with the clinical features. METHODS: Thirty-one blebs of 24 patients underwent noncontact in vivo confocal microscopy using the

Characteristics of Cl- uptake in rat alveolar type I cells.

2009-08-28T16:19:00.001-07:00

Am J Physiol Lung Cell Mol Physiol. 2009 Aug 14; Johnson M, Allen L, Dobbs LGAlthough Cl(-) transport in fetal lung is important for fluid secretion and normal lung development, the role of Cl(-) transport in adult lung is not well understood. In physiologic studies, the cystic fibrosis transmembrane regulator CFTR plays a role in fluid absorption in the distal airspaces of adult lung and

Isocitrate lyase supplies precursors for hydrogen cyanide production in a cystic fibrosis isolate of Pseudomonas aeruginosa.

2009-08-27T16:00:00.001-07:00

J Bacteriol. 2009 Aug 21; Hagins JM, Locy R, Silo-Suh LPseudomonas aeruginosa colonizes and can persist in the lungs of cystic fibrosis (CF) patients for decades. Adaptation of P. aeruginosa to the CF lung environment causes various genotypic and phenotypic alterations in the bacterium that facilitate persistence. We showed previously that isocitrate lyase (ICL) activity is constitutively

Genetic and Phenotypic Characteristics of Pleomorphic Lobular Carcinoma In Situ of the Breast.

2009-08-27T02:35:00.001-07:00

Am J Surg Pathol. 2009 Aug 20; Chen YY, Hwang ES, Roy R, Devries S, Anderson J, Wa C, Fitzgibbons PL, Jacobs TW, Macgrogan G, Peterse H, Vincent-Salomon A, Tokuyasu T, Schnitt SJ, Waldman FMThe clinical, pathologic, and molecular features of pleomorphic lobular carcinoma in situ (PLCIS) and the relationship of PLCIS to classic LCIS (CLCIS) are poorly defined. In this study, we analyzed 31 cases

Immunology of whales and dolphins.

2009-08-26T16:11:00.001-07:00

Vet Immunol Immunopathol. 2009 Aug 3; Beineke A, Siebert U, Wohlsein P, BaumgÃ¤rtner WThe increasing disease susceptibility in different whale and dolphin populations has led to speculation about a possible negative influence of environmental contaminants on the immune system and therefore on the health status of marine mammals. Despite current efforts in the immunology of marine mammals several

Oral contraceptives for functional ovarian cysts.

2009-08-25T15:50:00.001-07:00

Obstet Gynecol. 2009 Sep; 114(3): 679-80BACKGROUND:: Functional ovarian cysts are a common gynecological problem among women of reproductive age worldwide. When large, persistent, or painful, these cysts may require operations, sometimes resulting in removal of the ovary. Since early oral contraceptives were associated with a reduced incidence of functional ovarian cysts, many clinicians

Choledochal Cysts in Children and Adults with Contrasting Profiles: 11-Year Experience at a Tertiary Care Center in Kashmir.

2009-08-25T02:25:00.001-07:00

World J Surg. 2009 Aug 22; Shah OJ, Shera AH, Zargar SA, Shah P, Robbani I, Dhar S, Khan ABBACKGROUND: Choledochal cyst is a surgical problem usually related to infancy and childhood. Despite advancements in management, a large number of cases still present during adulthood. The clinical course and outcome in children varies from that in adults. This study focuses on these variations in terms of

Update on new pulmonary therapies.

2009-08-24T23:01:00.001-07:00

Curr Opin Pulm Med. 2009 Aug 19; Retsch-Bogart GZPURPOSE OF REVIEW: Understanding the molecular and cellular processes responsible for the development of lung disease in cystic fibrosis (CF) has led to evaluation of a broad range of new therapies within multiple therapeutic classes. For these reasons, clinical research in CF is accelerating, as new agents progress through the early stages of

Female boxing in Italy: 2002-2007 report.

2009-08-24T16:14:00.001-07:00

Br J Sports Med. 2009 Aug 19; Bianco M, Sanna N, Bucari S, Fabiano C, Palmieri V, Zeppilli POBJECTIVE: to collect medical data on women's boxing. DESIGN: Cross-sectional and longitudinal study. SETTING: Medical examinations requested by Italian laws. PARTICIPANTS: A retrospective study was conducted on all female boxing competitions in Italy from April 2001 to December 2007. Sixty-one amateur

18-Fluorodeoxyglucose-PET/CT Imaging of Lungs in Patients With Cystic Fibrosis.

2009-08-24T08:20:00.001-07:00

Chest. 2009 Aug 20; Klein M, Cohen-Cymberknoh M, Armoni S, Shoseyov D, Chisin R, Orevi M, Freedman N, Kerem EBACKGROUND: Airway inflammation plays a critical role in the progression of cystic fibrosis (CF) lung disease and in the destruction of airways and lung parenchyma. Current methods to assess CF lung disease, (BAL, spirometry, HRCT), do not always accurately reflect actual disease states.

Health Related Quality of Life of a Tertiary Referral Center Population With Urinary Incontinence Using the DCGM-10 Questionnaire.

2009-08-23T23:29:00.001-07:00

J Urol. 2009 Aug 18; Bachmann C, Lehr D, Janhsen E, Sambach H, Muehlan H, Gontard AV, Bachmann HPURPOSE: We evaluated health related quality of life of pediatric patients with nonneurogenic urinary incontinence and determined potential influencing factors. Also, health related quality of life results in our sample were compared to those of other chronic childhood health conditions. MATERIALS AND

The association of host age and gender with inflammation around neurocysticercosis cysts.

2009-08-23T07:23:00.001-07:00

Ann Trop Med Parasitol. 2009 Sep; 103(6): 487-99Kelvin EA, Carpio A, Bagiella E, Leslie D, Leon P, Andrews H, Hauser WA, The results of previous investigations indicate that age and gender may influence the strength of the human host's immune response to infection of the central nervous system with the larvae of Taenia solium. Most of the relevant research on such neurocysticercosis (NCC) has,

Comparative performance of MDCT and MRI with MR cholangiopancreatography in characterizing small pancreatic cysts.

2009-08-23T00:17:00.001-07:00

AJR Am J Roentgenol. 2009 Sep; 193(3): 722-31Sainani NI, Saokar A, Deshpande V, FernÃ¡ndez-del Castillo C, Hahn P, Sahani DVOBJECTIVE: The objective of our study was to compare MDCT with MRI-MR cholangiopancreatography (MRCP) in characterizing small pancreatic cysts (< or = 3 cm) and predicting aggressiveness. MATERIALS AND METHODS: In a retrospective analysis, contrast-enhanced MDCT and MRI

Magnetic resonance imaging analysis of the bioabsorbable Milagro interference screw for graft fixation in anterior cruciate ligament reconstruction.

2009-08-22T21:30:00.001-07:00

Strategies Trauma Limb Reconstr. 2009 Aug 21; Frosch KH, Sawallich T, SchÃ¼tze G, Losch A, Walde T, Balcarek P, Konietschke F, StÃ¼rmer KMLigament graft fixation with bioabsorbable interference screws is a standard procedure in cruciate ligament replacement. Previous screw designs may resorb incompletely, and can cause osteolysis and sterile cysts despite being implanted for several years. The

Laparoscopic-assisted transgastric cholecystectomy and secure endoscopic closure of the transgastric defect in a survival porcine model.

2009-08-22T17:49:00.001-07:00

Endoscopy. 2009 Aug 14; Arezzo A, Kratt T, Schurr MO, Morino MBACKGROUND AND STUDY AIMS: Natural orifice transluminal endoscopic surgery holds promise for surgical interventions. Before the feasibility of this technique can be established, however, secure sealing of the transluminal access needs to be thoroughly investigated. PATIENTS AND METHODS: Following antibiotic prophylaxis and gastric

Staphylococcus aureus Nasal Colonization Among Pediatric CF Patients and Their Household Contacts.

2009-08-21T18:53:00.001-07:00

Pediatr Infect Dis J. 2009 Aug 14; Stone A, Quittell L, Zhou J, Alba L, Bhat M, Decelie-Germana J, Rajan S, Bonitz L, Welter JJ, Dozor AJ, Gherson I, Lowy FD, Saiman LBACKGROUND:: Little is known about the prevalence of Staphylococcus aureus nasal colonization and the epidemiology of methicillin-susceptible and methicillin-resistant S. aureus (MRSA) among cystic fibrosis (CF) patients and their

Diagnostic accuracy of transvaginal ultrasound examination for assigning a specific diagnosis to adnexal masses.

2009-08-20T20:54:00.001-07:00

Ultrasound Obstet Gynecol. 2009 Aug 17; Sokalska A, Timmerman D, Testa AC, Van Holsbeke C, Lissoni AA, Leone FP, Jurkovic D, Valentin LOBJECTIVES: To determine the sensitivity and specificity of subjective evaluation of gray-scale and Doppler ultrasound findings (here called pattern recognition) when used by experienced ultrasound examiners with regard to making a specific diagnosis of adnexal

A Prospective Diagnostic Accuracy Study of 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography, Multidetector Row Computed Tomography, and Magnetic Resonance Imaging in Primary Dia

2009-08-20T17:48:00.000-07:00

Ann Surg. 2009 Aug 14; Kauhanen SP, Komar G, SeppÃ¤nen MP, Dean KI, Minn HR, Kajander SA, Rinta-Kiikka I, Alanen K, Borra RJ, Puolakkainen PA, Nuutila P, Ovaska JTOBJECTIVE:: To prospectively compare the accuracy of combined positron emission tomography/computed tomography using F-fluorodeoxyglucose (FDG-PET/CT), multidetector row computed tomography (MDCT), and magnetic resonance imaging (MRI)

Contralateral coronoid hyperplasia in patients undergoing hemimandibulectomy with disarticulation: a case series.

2009-08-20T07:42:00.001-07:00

J Oral Maxillofac Surg. 2009 Sep; 67(9): 1821-5Jamal BT, Taub D, Gold LPURPOSE: The purpose of this article is to evaluate whether hemimandibulectomy with disarticulation predisposes the patient to the development of contralateral coronoid hyperplasia, thereby justifying a coronoidectomy procedure for these patients to improve jaw function and mouth opening and decrease the length of

Characterization of the ovarian and reproductive abnormalities in prepubertal and adult estrogen non-responsive estrogen receptor alpha knock-in (ENERKI) mice.

2009-08-20T00:05:00.001-07:00

Steroids. 2009 Jul 22; Sinkevicius KW, Woloszyn K, Laine M, Jackson KS, Greene GL, Woodruff TK, Burdette JEEstrogen non-responsive estrogen receptor alpha (ERalpha) knock-in (ENERKI) mice have a mutation (glycine 525 to leucine, G525L) in the ligand-binding domain of ERalpha. The mutant ERalpha protein has a significantly lower affinity and response to endogenous estrogens, while not altering

Differential expression of collagen type V and XI alpha-1 in human ascending thoracic aortic aneurysms.

2009-08-19T21:59:00.001-07:00

Ann Thorac Surg. 2009 Aug; 88(2): 506-13Toumpoulis IK, Oxford JT, Cowan DB, Anagnostopoulos CE, Rokkas CK, Chamogeorgakis TP, Angouras DC, Shemin RJ, Navab M, Ericsson M, Federman M, Levitsky S, McCully JDBACKGROUND: The molecular mechanisms leading to ascending thoracic aortic aneurysms (ATAAs) remain unknown. We hypothesized that alterations in expression levels of specific fibrillar collagens

Methylation frequencies of cell-cycle associated genes in epithelial odontogenic tumours.

2009-08-19T17:34:00.001-07:00

Arch Oral Biol. 2009 Aug 11; Moreira PR, GuimarÃ£es MM, Gomes CC, Diniz MG, Brito JA, Castro WH, Gomez RSOBJECTIVE: The benign epithelial odontogenic tumours constitute a group of lesions derived from epithelial elements of the tooth-forming apparatus. This group includes lesions of different biological behaviour, such as ameloblastoma, calcifying cystic odontogenic tumour (CCOT) and adenomatoid

Receptor tyrosine phosphatases control tracheal tube geometries through negative regulation of Egfr signaling.

2009-08-19T00:29:00.001-07:00

Development. 2009 Aug 12; Jeon M, Zinn KThe formation of epithelial tubes with defined shapes and sizes is essential for organ development. We describe a unique tracheal tubulogenesis phenotype caused by loss of both Drosophila type III receptor tyrosine phosphatases (RPTPs), Ptp4E and Ptp10D. Ptp4E is the only widely expressed Drosophila RPTP, and is the last of the six fly RPTPs to be

Antibacterial activities of a fosfomycin/tobramycin combination: a novel inhaled antibiotic for bronchiectasis.

2009-08-18T02:20:00.001-07:00

J Antimicrob Chemother. 2009 Aug 13; Macleod DL, Barker LM, Sutherland JL, Moss SC, Gurgel JL, Kenney TF, Burns JL, Baker WRObjectives To compare the in vitro and in vivo activities of a 4:1 (w/w) fosfomycin/tobramycin combination (FTI) with those of fosfomycin and tobramycin alone against cystic fibrosis (CF) and non-CF bronchiectasis pathogens. Methods Clinical isolates of CF Pseudomonas

Conditional Deletion of Dnaic1 in a Murine Model of Primary Ciliary Dyskinesia Causes Chronic Rhinosinusitis.

2009-08-17T23:25:00.001-07:00

Am J Respir Cell Mol Biol. 2009 Aug 12; Ostrowski LE, Yin W, Rogers TD, Busalacchi KB, Chua M, O'Neal WK, Grubb BRStudies of Primary Ciliary Dyskinesia (PCD) have been hampered by the lack of a suitable animal model because disruption of essential ciliary genes in mice results in a high incidence of lethal hydrocephalus. To develop a viable mouse model for long-term studies of PCD, we have

Significance of cytomorphological and microbiological examination of bile collected by endoscopic cannulation of the papilla of vater.

2009-08-17T05:50:00.001-07:00

Indian J Pathol Microbiol. 2009 Jul-Sep; 52(3): 328-31Misra V, Misra SP, Singh PA, Dwivedi M, Verma K, Narayan UBACKGROUND: Bile analysis yields important information such as "biliary microlithiasis" and biliary tract colonization by microorganisms like Salmonella typhi or paratyphi, Escherichia coli, etc., which may progresses to cholelithiasis and have been found to have a role in the

Noncardiac pathology on clinical cardiac magnetic resonance imaging.

2009-08-16T22:58:00.001-07:00

JACC Cardiovasc Imaging. 2009 Aug; 2(8): 980-6Chan PG, Smith MP, Hauser TH, Yeon SB, Appelbaum E, Rofsky NM, Manning WJOBJECTIVES: We sought to determine the prevalence of noncardiac pathology in a large consecutive series of patients referred for clinical cardiac magnetic resonance (CMR) studies. BACKGROUND: The imaging field for many CMR sequences extends outside of the heart border. As a

Benign bone cyst mimicking skeletal metastasis on (18)F-FDG-PET.

2009-08-15T22:56:00.001-07:00

Hell J Nucl Med. 2009 May-Aug; 12(2): 179-80Khurana A, Jaimini A, Tripathi M, Mondal ATo the Editor: We read with interest in Hell J Nucl Med the letter by Seven B. et al. on: "Aneurysmal bone cyst of the second metatarsal: three-phase bone scan findings and radiological assessment" published in 2008; 11(3): 189-190. We now report another case of "active/viable" bone cyst shown in the fluorine-

Adenoid Cystic Carcinoma-Like Pattern in Spiradenoma and Spiradenocylindroma: A Rare Feature in Sporadic Neoplasms and Those Associated With Brooke-Spiegler Syndrome.

2009-08-13T17:36:00.001-07:00

Am J Dermatopathol. 2009 Jul 23; Petersson F, Kutzner H, Spagnolo DV, Bisceglia M, Kacerovska D, Vazmitel M, Michal M, Kazakov DVSpiradenoma is a benign, morphologically well-defined cutaneous adnexal neoplasm that is closely related to cylindroma. We present the rare occurrence of adenoid cystic carcinoma (ACC)-like areas in 7 spiradenomas and 1 spiradenocylindroma, not described in the English

Laparoscopic Decortication of Large Renal Cysts: A Comparison Between the Transperitoneal and Retroperitoneal Approaches.

2009-08-12T17:35:00.001-07:00

J Laparoendosc Adv Surg Tech A. 2009 Aug 1; Ryu DS, Oh THAbstract Background: We compared the operative outcomes and follow-up results of laparoscopic decortication of large, simple renal cysts, performed by the transperitoneal (TP) and retroperitoneal (RP) approaches, and identified selection criteria for each approach. Materials and Methods: Between 2000 and 2007, 53 patients with renal cysts

Radiographic size versus surgical size of renal masses: Which is the true size of the tumor?

2009-08-12T06:37:00.001-07:00

J BUON. 2009 Apr-Jun; 14(2): 235-8Alicioglu B, Kaplan M, Yurut-Caloglu V, Usta U, Levent SPurpose: The size of a renal neoplasm is important for staging, prognosis and selection of appropriate treatment. Our aim was to determine whether there is a discrepancy between the radiographic and pathological size of renal tumors. Patients and methods: The maximum size of 35 resected renal tumors was

[Pathophysiology and immune response in sheep experimentally infected with Echinococcus granulosus.]

2009-08-11T18:39:00.001-07:00

Medicina (B Aires). 2009; 69(3): 341-6Larrieu E, Alvarez AR, Gatti A, Mancini S, Bigatti R, Araya D, Vespoli V, GarcÃa Vinet J, GarcÃa Cacheau M, Alvarez E, Cavagion LThe immune response to Echinococcus granulosus in sheep has not been extensively investigated. The objective of this study was to increase the information on the physiopathology of E. granulosus and the immune response elicited

Endoscopic treatment of middle fossa arachnoid cysts: a series of 40 patients treated endoscopically in two centres.

2009-08-11T07:22:00.001-07:00

Childs Nerv Syst. 2009 Jul 24; Spacca B, Kandasamy J, Mallucci CL, Genitori LPURPOSE: Middle fossa arachnoid cysts (MFAC) are a relatively common, benign pathology that pose a therapeutic challenge for both symptomatic and asymptomatic patients. The optimal surgical strategy and indication to treat are still debated by neurosurgeons. We reviewed our experience and results in a group of patients

Provision of contraception services and advice for women with cystic fibrosis.

2009-08-11T02:03:00.001-07:00

J Fam Plann Reprod Health Care. 2009 Jul; 35(3): 157-60Gatiss S, Mansour D, Doe S, Bourke SBACKGROUND AND METHODOLOGY: As the prognosis of patients with cystic fibrosis (CF) improves, issues of sexual health, fertility, pregnancy and contraception are increasingly important. In order to plan the provision of a contraception and sexual health service for women with CF we studied their sexual and

Pancreatic ductal adenocarcinoma with intratumoral cystic lesions on MRI: correlation with histopathological findings.

2009-08-10T23:17:00.001-07:00

Br J Radiol. 2009 Jul 20; Yoon SE, Byun JH, Kim KA, Kim HJ, Lee SS, Jang SJ, Jang YJ, Lee MGThe purpose of this study was to evaluate intratumoral cystic lesions of pancreatic ductal adenocarcinoma (PDAC) depicted on MRI, and to correlate these cystic lesions with their histopathological findings. This study included 12 patients (7 males and 5 females; mean age, 59 years) with intratumoral

Supratentorial abnormalities in the Chiari II malformation, III: The interhemispheric cyst.

2009-08-10T07:36:00.001-07:00

J Ultrasound Med. 2009 Aug; 28(8): 999-1006Wong SK, Barkovich AJ, Callen AL, Filly RAOBJECTIVE: Our clinical observations noted an interhemispheric "cyst," a protrusion of the posterior superior third ventricle, in fetuses with myelomeningocele (MMC). The study analyzed the frequency of this observation and features that influence its visualization. METHODS: We searched for cases of fetal MMC

Airway Surface Liquid Contains Endogenous DNase Activity which Can be Activated by Exogenous Magnesium.

2009-08-09T23:19:00.001-07:00

Eur J Med Res. 2009 Jul 22; 14(7): 304-8Rosenecker J, Naundorf S, Rudolph CIntroduction: The removal of highly viscous mucus from the airways is an important task in the treatment of chronic lung disease like in cystic fibrosis. The inhalation of recombinant human DNase- I (rhDNase-I) is used to facilitate the removal of tenacious airway secretions in different lung diseases and especially in CF

Asymptomatic congenital cystic adenomatoid malformation of the lung: Is it time to operate?

2009-08-09T17:25:00.000-07:00

J Thorac Cardiovasc Surg. 2009 Mar 25; Conforti A, Aloi I, Trucchi A, Morini F, Nahom A, Inserra A, Bagolan POBJECTIVE: The optimal management of congenital adenomatoid malformation of the lung remains controversial. Prenatal ultrasonographic analysis has increasingly discovered asymptomatic lesions, raising questions about the need for and timing of surgical treatment for asymptomatic

Caenorhabditis elegans Semi-Automated Liquid Screen Reveals a Specialized Role for the Chemotaxis Gene cheB2 in Pseudomonas aeruginosa Virulence.

2009-08-09T15:41:00.001-07:00

PLoS Pathog. 2009 Aug; 5(8): e1000540Garvis S, Munder A, Ball G, de Bentzmann S, Wiehlmann L, Ewbank JJ, TÃ¼mmler B, Filloux APseudomonas aeruginosa is an opportunistic human pathogen that causes infections in a variety of animal and plant hosts. Caenorhabditis elegans is a simple model with which one can identify bacterial virulence genes. Previous studies with C. elegans have shown that

Modifier gene study of meconium ileus in cystic fibrosis: statistical considerations and gene mapping results.

2009-08-09T07:19:00.001-07:00

Hum Genet. 2009 Aug 7; Dorfman R, Li W, Sun L, Lin F, Wang Y, Sandford A, ParÃ© PD, McKay K, Kayserova H, Piskackova T, Macek M, Czerska K, Sands D, Tiddens H, Margarit S, Repetto G, Sontag MK, Accurso FJ, Blackman S, Cutting GR, Tsui LC, Corey M, Durie P, Zielenski J, Strug LJCystic fibrosis (CF) is a monogenic disease due to mutations in the CFTR gene. Yet, variability in CF disease

Outcome and treatment in an antenatally diagnosed congenital cystic adenomatoid malformation of the lung.

2009-08-09T06:56:00.001-07:00

Pediatr Surg Int. 2009 Aug 7; Nagata K, Masumoto K, Tesiba R, Esumi G, Tsukimori K, Norio W, Taguchi TBACKGROUND: The natural history of patients with antenatally diagnosed congenital cystic adenomatoid malformation of the lung (CCAM) is still fully unknown. In symptomatic patients with respiratory distress, an operation is performed during the neonatal period. However, in asymptomatic patients,

Laparoscopic Simultaneous Treatment of Peripelvic Renal Cysts and Stones: Case Series.

2009-08-08T01:04:00.001-07:00

J Endourol. 2009 Jul 20; Micali S, Pini G, Sighinolfi MC, De Stefani S, Annino F, Bianchi GAbstract Introduction: Renal multiple peripelvic cysts are often symptomatic. Obstruction of renal hilum and the collecting system leads to hydronephrosis and could promote formation of stones. Managing both entities at the same time needs a new approach to minimize complications and improve success rates.

Adverse events arising from a palliative care survey.

2009-08-07T16:13:00.001-07:00

Palliat Med. 2009 Jul 31; Braithwaite M, Philip J, Finlayson F, Tranberg H, Gold M, Kotsimbos T, Wilson JDevelopment of evidence-based practice requires investigation of the attitudes and needs of patients, families and healthcare professionals, particularly for sensitive subject areas. Cystic fibrosis (CF) is a recessively inherited life-limiting disorder resulting in early death. Patients with

Symptomatic intracystic hemorrhage in pineal cysts.

2009-08-06T02:32:00.001-07:00

J Neurosurg Pediatr. 2009 Aug; 4(2): 130-6Sarikaya-Seiwert S, Turowski B, HÃ¤nggi D, Janssen G, Steiger HJ, Stummer WPineal cysts are benign and often asymptomatic intracranial entities. Occasionally they can lead to neurological symptoms through growth or due to intracystic hemorrhage. The purpose of the current report is to describe their clinical characteristics and treatment options. In the

Asymptomatic pancreatic cystic neoplasm: a cost-effectiveness analysis of different strategies of management.

2009-08-05T17:54:00.001-07:00

Gastrointest Endosc. 2009 Jul 30; Das A, Ngamruengphong S, Nagendra S, Chak ABACKGROUND: Optimal management of asymptomatic pancreatic cystic neoplasm is not known. OBJECTIVE: In a decision analysis, the cost-effectiveness of different strategies for managing solitary, asymptomatic pancreatic cystic neoplasm were compared. INTERVENTION: Three strategies were examined in a Markov model with a

Limitations of the Murine Nose in the Development of Non-viral Airway Gene Transfer.

2009-08-04T17:34:00.001-07:00

Am J Respir Cell Mol Biol. 2009 Jul 31; Griesenbach U, Sumner-Jones SG, Holder E, Munkonge FM, Wodehouse T, Smith SN, Wasowicz MY, Pringle I, Casamayor I, Chan M, Coles R, Cornish N, Dewar A, Doherty A, Farley R, Green AM, Jones BL, Larsen MD, Lawton AE, Manvell M, Painter H, Singh C, Somerton L, Stevenson B, Varathalingam A, Siegel C, Scheule RK, Cheng SH, Davies JC, Porteous DJ, Gill DR, Boyd

Adjuvant Chemoradiotherapy After Pancreatic Resection for Invasive Carcinoma Associated with Intraductal Papillary Mucinous Neoplasm of the Pancreas.

2009-08-04T04:49:00.001-07:00

Int J Radiat Oncol Biol Phys. 2009 Jul 31; Swartz MJ, Hsu CC, Pawlik TM, Winter J, Hruban RH, Guler M, Schulick RD, Cameron JL, Laheru DA, Wolfgang CL, Herman JMPURPOSE: Intraductal papillary mucinous neoplasms are mucin-producing cystic neoplasms of the pancreas. One-third are associated with invasive carcinoma. We examined the benefit of adjuvant chemoradiotherapy (CRT) for this cohort.

Loss of GATA4 and GATA6 expression specifies ovarian cancer histological subtypes and precedes neoplastic transformation of ovarian surface epithelia.

2009-08-04T03:12:00.001-07:00

PLoS One. 2009; 4(7): e6454Cai KQ, Caslini C, Capo-chichi CD, Slater C, Smith ER, Wu H, Klein-Szanto AJ, Godwin AK, Xu XXBACKGROUND: The family of zinc finger-containing GATA transcription factors plays critical roles in cell lineage specification during early embryonic development and organ formation. GATA4 and GATA6 were found to be frequently lost in ovarian cancer, and the loss is proposed

[Report of the National Renal Ultrasound Study Group on the ultrasound activity of nephrology care units in Italy.]

2009-08-03T21:09:00.001-07:00

G Ital Nefrol. 2009 Jul-Aug; 26(4): 523-9Petrarulo F, Alberghini E, Capotondo L, Logias F, Melfa G, Mancini AThe presence of operational and organizational differences in the use of ultrasonography in Italian nephrology units has prompted this survey on a nationwide scale. The survey was carried out by questionnaire and included questions about the activity and equipment of each nephrology unit,

Percutaneous treatment of lymphatic malformations.

2009-08-03T20:44:00.001-07:00

Otolaryngol Head Neck Surg. 2009 Aug; 141(2): 219-224Shiels WE, Kang DR, Murakami JW, Hogan MJ, Wiet GJOBJECTIVE: The aim of this study is to investigate a new treatment regimen for macrocystic and microcystic lymphatic malformations (LM) of the head and neck. STUDY DESIGN: The study represents a retrospective review of outcomes from new percutaneous treatments for lymphatic malformations.

Adenosine receptors, cystic fibrosis, and airway hydration.

2009-08-03T18:04:00.001-07:00

Handb Exp Pharmacol. 2009; 363-81Com G, Clancy JPAdenosine (Ado) regulates diverse cellular functions in the lung through its local production, release, metabolism, and subsequent stimulation of G-protein-coupled P1 purinergic receptors. The A(2B) adenosine receptor (A(2B)AR) is the predominant P1 purinergic receptor isoform expressed in surface airway epithelia, and Ado is an important

Diplopia and Fluoroquinolones.

2009-08-03T01:23:00.001-07:00

Ophthalmology. 2009 Jul 28; Fraunfelder FW, Fraunfelder FTPURPOSE: To report a possible association between fluoroquinolones and diplopia. DESIGN: Database study. PARTICIPANTS: A total of 171 subjects were studied. METHODS: Spontaneous reports from the National Registry of Drug-Induced Ocular Side Effects, World Health Organization, and Food and Drug Administration were collected on

Synaptic scaffolding molecule binds to and regulates vasoactive intestinal polypeptide type-1 receptor in epithelial cells.

2009-08-02T17:43:00.001-07:00

Gastroenterology. 2009 Aug; 137(2): 607-17, 617.e1-4Gee HY, Kim YW, Jo MJ, Namkung W, Kim JY, Park HW, Kim KS, Kim H, Baba A, Yang J, Kim E, Kim KH, Lee MGBACKGROUND & AIMS: Vasoactive intestinal polypeptide (VIP) is a principal regulator of fluid and electrolyte secretion in the gastrointestinal system. The VIP type-1 receptor (VPAC1), a class II G-protein-coupled receptor, contains a putative

The expression of the o-linked n-acetylglucosamine containing epitope H in the gemistocytic, pilocytic and subependymal giant cell astrocytomas.

2009-08-02T15:52:00.001-07:00

Oncol Rep. 2009 Sep; 22(3): 521-4Arvanitis LD, Koukoulis GK, Kanavaros PThe epitope H contains an O-linked N-acetylglucosamine residue in a specific conformation and/or environment recognized by the monoclonal antibody H. It has previously been shown that the epitope H is present in several types of normal and pathological cells and in several polypeptides. In normal human brains the epitope H

Diffusion-weighted Imaging Characteristics of Primary Central Nervous System Germinoma with Histopathologic Correlation A Retrospective Study(1).

2009-08-02T07:29:00.001-07:00

Acad Radiol. 2009 Jul 28; Douglas-Akinwande AC, Ying J, Momin Z, Mourad A, Hattab EMRATIONALE AND OBJECTIVES: The aim of this study was to quantify, using diffusion-weighted magnetic resonance imaging, the microscopic rate of water diffusion in pure germinoma and to determine whether or not the apparent diffusion coefficient (ADC) values correlated with the different histologic components.

Evaluation of Injection Frequency and Visual Acuity Outcomes for Ranibizumab Monotherapy in Exudative Age-related Macular Degeneration.

2009-08-02T06:26:00.001-07:00

Ophthalmology. 2009 Jul 28; Dadgostar H, Ventura AA, Chung JY, Sharma S, Kaiser PKOBJECTIVE: To evaluate the visual outcomes for intravitreal ranibizumab administered on an as-needed basis for exudative age-related macular degeneration (AMD) and to investigate the relationship between injection frequency and visual outcome in this setting. DESIGN: Retrospective, interventional case series.

Home intravenous antibiotic treatment for acute pulmonary exacerbations in cystic fibrosis - Is it good for the patient?

2009-08-02T00:45:00.001-07:00

Ann Thorac Med. 2009 Jul; 4(3): 111-4Sequeiros IM, Jarad NAThere is a worldwide drive for the home management of chronic respiratory diseases. With the widespread use of home intravenous (IV) treatment for cystic fibrosis (CF) pulmonary exacerbations (PExs), evidence pointing to an inferior outcome of care for home-treated patients in comparison to hospital-treated patients is a cause of concern

Modelling the age variation of larval protoscoleces of Echinococcus granulosus in sheep.

2009-07-31T20:48:00.001-07:00

Int J Parasitol. 2009 Feb 4; Torgerson PR, Ziadinov I, Aknazarov D, Nurgaziev R, Deplazes PIn autumn 2006, a study of the age-dynamics of Echinoccus granulosus cyst abundance was undertaken from an abattoir study of 1,081 sheep slaughtered in Naryn Province in central Kyrgyzstan, an area endemic for echinococcosis. The results demonstrated approximately 64% of sheep were infected with the

Effectiveness of a family-oriented rehabilitation program on the quality of life of parents of chronically ill children.

2009-07-31T17:53:00.001-07:00

Klin Padiatr. 2009 Jul-Aug; 221(4): 241-6West CA, Besier T, Borth-Bruhns T, Goldbeck LBACKGROUND: Parents of chronically ill children face numerous burdens in daily life, which can impair their quality of life (QoL) significantly. Therefore in family-oriented rehabilitation, not only the children themselves, but also their parents receive interventions. These aim at stabilizing parents both

Molecular and morphological characterisation of Echinococcus from food producing animals in India.

2009-07-30T20:59:00.001-07:00

Vet Parasitol. 2009 Jun 24; Pednekar RP, Gatne ML, Thompson RC, Traub RJIn view of the medical, veterinary and economic importance of hydatid disease in India, our study aimed to determine the prevalence and genotypes of Echinococcus present in domestic livestock in India. Out of 21,861 animals examined, cattle were found with the highest prevalence of hydatid cysts (5.10%) followed by buffaloes

GCDFP-15 Positive and TTF-1 Negative Primary Lung Neoplasms: A Tissue Microarray Study of 381 Primary Lung Tumors.

2009-07-30T17:27:00.001-07:00

Appl Immunohistochem Mol Morphol. 2009 Jul 17; Wang LJ, Greaves WO, Sabo E, Noble L, Tavares R, Ng T, Delellis RA, Resnick MBGross cystic disease fluid protein (GCDFP-15) is currently used as an immunohistochemical marker of breast cancer, whereas thyroid transcription factor (TTF-1) is commonly used as a marker of primary lung neoplasms. Traditionally, a GCDFP-15+/TTF-1- immunohistochemical

Future cystic fibrosis treatment, gene therapy

2009-07-30T06:22:00.000-07:00

Cystic fibrosis is a hereditary disease that affects one in every 2500 live births. It is the most common genetic disease of whites and one in 25 people carries the gene that causes the disease.Affected individuals have a reduced life expectancy, although in recent years has increased the average years to live.For a newborn child inheriting the disease, both parents must be carriers of the

Acid Sphingomyelinase Inhibitors Normalize Pulmonary Ceramide and Inflammation in Cystic Fibrosis.

2009-07-30T05:51:00.000-07:00

Am J Respir Cell Mol Biol. 2009 Jul 27; Becker KA, RiethmÃ¼ller J, LÃ¼th A, DÃ¶ring G, Kleuser B, Gulbins EBackground: Employing genetic mouse models we have recently shown that ceramide accumulation is critically involved in the pathogenesis of cystic fibrosis (CF) lung disease. Rationale: Genetic or systemic inhibition of the acid sphingomyelinase (Asm) is not feasible for treatment of

Genetic categorization of Echinococcus granulosus from humans and herbivorous hosts in Iran using an integrated mutation scanning-phylogenetic approach.

2009-07-30T02:38:00.001-07:00

Electrophoresis. 2009 Jul 27; Sharbatkhori M, Mirhendi H, Jex AR, Pangasa A, Campbell BE, Kia EB, Eshraghian MR, Harandi MF, Gasser RBIn the present study, we have extended earlier taxonomic, biochemical and experimental investigations to characterize Echinococcus granulosus from various hosts in Iran utilizing DNA regions (designated pcox1 and pnad1) within the cytochrome c oxidase subunit 1

Involvement of pmrAB and phoPQ in polymyxin B adaptation and inducible resistance in non-cystic fibrosis clinical isolates of Pseudomonas aeruginosa.

2009-07-29T22:53:00.001-07:00

Antimicrob Agents Chemother. 2009 Jul 27; Schurek KN, Sampaio JL, Kiffer CR, Sinto S, Mendes CM, Hancock REWhen investigating susceptibility testing methods for polymyxins, 24 multidrug resistant clinical isolates of Pseudomonas aerugionsa were observed to have a distinct, reproducible phenotype in which skipped wells were observed during microbroth dilution testing for polymyxin B. Possible

Histologically Bland "Extremely Well Differentiated" Thyroid Carcinomas Arising in Struma Ovarii can Recur and Metastasize.

2009-07-29T17:28:00.001-07:00

Int J Gynecol Pathol. 2009 May; 28(3): 222-30Garg K, Soslow RA, Rivera M, Tuttle MR, Ghossein RAStruma ovarii (SO) infrequently harbor carcinomas that are histologically similar to those arising in the eutopic thyroid. We identified 10 such cases in our files. Eight patients presented with pelvic-related symptoms whereas 2 were incidentally discovered during pregnancy, all with disease confined

Aicardi-Goutieres Syndrome: Neuroradiologic Findings and Follow-Up.

2009-07-29T06:36:00.001-07:00

AJNR Am J Neuroradiol. 2009 Jul 23; Uggetti C, La Piana R, Orcesi S, Egitto MG, Crow YJ, Fazzi EBACKGROUND AND PURPOSE: To date, few studies have focused specifically on imaging findings in Aicardi-GoutiÃ¨res syndrome (AGS). We set out to evaluate retrospectively neuroradiologic data from a large sample of patients with AGS, focusing on the pattern of white matter abnormalities and the temporal

Obturatory abscess and pelvic pain caused by Brucella melitensis]

2009-07-29T02:30:00.001-07:00

Brucellosis which is a systemic infection, is seen endemically in Turkey. Although there a lot of complications related to brucellosis, soft tissue involvement is rare. In this case report a patient with mature cystic teratoma and a Brucella related obturatory abscess, was presented.A 21-year-old female patient with bilateral pelvic pain was admitted to the hospital with complaints of weakness,

Dysfunctional Cystic Fibrosis Transmembrane Conductance Regulator

2009-07-28T23:25:00.001-07:00

Cystic fibrosis is caused by mutated cystic fibrosis transmembrane conductance regulator (CFTR), and is characterized by robust airway inflammation and accumulation of apoptotic cells.Phagocytosis of apoptotic cells (efferocytosis) is a pivotal regulator of inflammation, because it prevents post-apoptotic necrosis and actively suppresses release of a variety of pro-inflammatory mediators,

A truncated CFTR protein rescues endogenous {Delta}F508-CFTR and corrects chloride transport in mice.

2009-07-28T18:55:00.001-07:00

FASEB J. 2009 Jul 20; Cormet-Boyaka E, Hong JS, Berdiev BK, Fortenberry JA, Rennolds J, Clancy JP, Benos DJ, Boyaka PN, Sorscher EJCystic fibrosis (CF) is most frequently associated with deletion of phenylalanine at position 508 (DeltaF508) in the CF transmembrane conductance regulator (CFTR) protein. The DeltaF508-CFTR mutant protein exhibits a folding defect that affects its processing and

Need for lung resection in patients with intact or ruptured hydatid cysts.

2009-07-28T17:30:00.001-07:00

Thorac Cardiovasc Surg. 2009 Aug; 57(5): 295-302Vasquez JC, Montesinos E, Peralta J, Rojas L, DeLaRosa J, Leon JJBACKGROUND: Lung hydatid cyst caused by ECHINOCOCCUS GRANULOSUS is endemic in many areas of the world. We aimed to compare the outcome of surgical treatment in intact and ruptured (infected or noninfected) cysts. METHODS: We reviewed the medical records of 115 patients with lung

Single-lung transplantation in patients with previous contralateral pneumonectomy: technical aspects and results.

2009-07-28T07:34:00.001-07:00

Eur J Cardiothorac Surg. 2009 Jul 24; Le Pimpec-Barthes F, Thomas PA, Bonnette P, Mussot S, Defrancquen P, Hernigou A, LatrÃ©mouille C, Riquet MObjective: Single-lung transplantation (SLTX) in patients with previous contralateral pneumonectomy (PN) is a rarely observed situation. Intrathoracic anatomical changes caused by mediastinal shift may complicate the surgical procedure. We collected

[Staphylococcus aureus hepatic abscess associated with cervical lymphadenitis]

2009-07-27T23:42:00.001-07:00

Mikrobiyol Bul. 2009 Apr; 43(2): 313-7DoÄan Celik A, YuluÄkural Z, KuloÄlu F, Akata FPyogenic liver abscesses usually develop secondary to biliary tract and intraabdominal infections and members of the Enterobacteriaceae family are usually implicated as the etiologic agents. In this report a case of hepatic abscess devoloped secondary to cervical lymphadenitis caused by Staphylococcus aureus,

[CT and MRI manifestations of pediatric presacral tumors.]

2009-07-27T15:52:00.001-07:00

Ai Zheng. 2009 Apr; 28(4): 420-4Fan M, Peng Q, Wang XY, Meng QF, Li ZPBackground and Objective: The imaging of presacral tumors in children is characteristic. Computed tomography (CT) and magnetic resonance imaging (MRI) have great values in identifying the position, contents and invasion of pediatric presacral tumors before operation. This study was to investigate the CT and MRI features of

Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.

2009-07-26T23:31:00.001-07:00

PLoS Genet. 2009 Jul; 5(7): e1000575Vincent DF, Yan KP, Treilleux I, Gay F, Arfi V, Kaniewsky B, Marie JC, Lepinasse F, Martel S, Goddard-Leon S, Iovanna JL, Dubus P, Garcia S, Puisieux A, Rimokh R, Bardeesy N, Scoazec JY, Losson R, Bartholin LInactivation of the Transforming Growth Factor Beta (TGFbeta) tumor suppressor pathway contributes to the progression of Pancreatic Ductal AdenoCarcinoma

Prevalent breast cancer patients with a homozygous mutant status

2009-07-15T15:56:00.001-07:00

Retrospective studies suggest that single nucleotide polymorphisms in the cytochrome P450 2D6 (CYP2D6) gene predict reduced tamoxifen metabolism, better tolerance and worse treatment outcome.We hypothesized that women with this genotype lack tamoxifen-induced endometrial and biochemical changes in follicle-stimulating hormone (FSH) and sex hormone-binding globulin (SHBG). We identified 56 breast

Using index of ventilation to assess response to treatment for acute pulmonary exacerbation in children with cystic fibrosis.

2009-07-15T15:35:00.001-07:00

Pediatr Pulmonol. 2009 Jul 13; Robinson PD, Cooper P, Van Asperen P, Fitzgerald D, Selvadurai HBACKGROUND: The use of alternative more sensitive measures has become a focus of research in CF. The utility of indexes of ventilation, Lung Clearance Index (LCI) and peak aerobic capacity (peak VO(2)), were studied as assessment tools in gauging response to intravenous (IV) therapy in acute pulmonary

Management of Ovarian Dermoid Cysts in the Pediatric and Adolescent Population.

2009-07-15T03:48:00.001-07:00

J Pediatr Adolesc Gynecol. 2009 Jul 7; Savasi I, Lacy JA, Ted Gerstle J, Stephens D, Kives S, Allen LSTUDY OBJECTIVE: To evaluate the surgical approach used in the management of ovarian dermoid cysts in the pediatric and adolescent population. DESIGN: A descriptive retrospective chart review of all cases of ovarian dermoid cyst excision between January 2001 and January 2006. SETTING: The

The recognition and treatment of growth disorders - A 50-year retrospective.

2009-07-14T15:22:00.001-07:00

Ann Hum Biol. 2009 Jul 10; 1-15Zemel BThe past 50 years have seen great progress in the understanding and treatment of classic growth disorders. Advances such as the recognition of hormone receptor defects, the development of recombinant growth hormone, and the expanding awareness of epigenetic phenomena affecting growth are among these great achievements. Yet growth failure remains a pervasive

Insulin Therapy to Improve BMI in Cystic Fibrosis Related Diabetes Without Fasting Hyperglycemia: Results of the CFRDT Trial.

2009-07-14T13:52:00.001-07:00

Diabetes Care. 2009 Jul 10; Moran A, Pekow P, Grover P, Zorn M, Slovis B, Pilewski J, Tullis E, Liou TG, Allen H, Objective: Cystic fibrosis related diabetes (CFRD) without fasting hyperglycemia (FH-) is not associated with microvascular or macrovascular complications, leading to controversy about the need for treatment. The CFRD Therapy Trial (CFRDT) sought to determine whether diabetes

[Sinonasal adenocarcinomas reviewed. Prognostic value of WHO 2005 histological classification.]

2009-07-14T05:36:00.001-07:00

Ann Otolaryngol Chir Cervicofac. 2009 Jul 8; El Ayoubi A, Poizat F, Garrel R, Costes V, Guerrier B, Essakalli L, Kzadri M, Crampette LOBJECTIVES: The WHO 2005 histological classification separates sinonasal adenocarcinoma (ADC) into three classes: intestinal-type adenocarcinoma (ITAC), low-grade sinonasal ADC and high-grade sinonasal ADC. The goal of this study was to check the relevance of this

N-acetyl resonances in in vivo and in vitro NMR spectroscopy of cystic ovarian tumors.

2009-07-14T02:39:00.001-07:00

NMR Biomed. 2009 Jul 10; Kolwijck E, Engelke UF, van der Graaf M, Heerschap A, Blom HJ, Hadfoune M, Buurman WA, Massuger LF, Wevers RAAn unassigned and prominent resonance in the region from delta 2.0-2.1 ppm has frequently been found in the in vivo MR spectra of cancer patients. We demonstrated the presence of this resonance with in vivo MRS in the cyst fluid of a patient with an ovarian tumor.

Life cycle and molecular phylogeny of the dinoflagellates Chytriodinium and Dissodinium, ectoparasites of copepod eggs.

2009-07-13T20:45:00.001-07:00

Eur J Protistol. 2009 Jul 7; GÃ³mez F, Moreira D, LÃ³pez-GarcÃa PThe dinoflagellates Chytriodinium affine, C. roseum and Dissodinium pseudolunula are ectoparasites of crustacean eggs. Here, we present new observations regarding their life cycle based on coastal plankton samples and incubations and analyze their molecular phylogeny using the small subunit ribosomal RNA gene (SSU rDNA) as a

Hepatic parenchyma resection using stapling devices: peri-operative and long-term outcome.

2009-07-13T18:09:00.001-07:00

HPB (Oxford). 2009; 11(1): 38-44Delis SG, Bakoyiannis A, Karakaxas D, Athanassiou K, Tassopoulos N, Manesis E, Ketikoglou I, Papakostas P, Dervenis CBACKGROUND: Stapler-assisted hepatectomy has not been well established, as a routine procedure, although few reports exist in the literature. This analysis assesses the safety and outcome of the method based on peri-operative data. MATERIALS AND

Prenatal exposure to bisphenol a at environmentally relevant doses adversely affects the murine female reproductive tract later in life.

2009-07-13T14:10:00.001-07:00

Environ Health Perspect. 2009 Jun; 117(6): 879-85Newbold RR, Jefferson WN, Padilla-Banks EBACKGROUND: Exposure to endocrine-disrupting chemicals during critical developmental periods causes adverse consequences later in life; an example is prenatal exposure to the pharmaceutical diethylstilbestrol (DES). Bisphenol A (BPA), an environmental estrogen used in the synthesis of plastics, is of

MRI findings of intracranial cystic meningiomas.

2009-07-12T18:22:00.001-07:00

Clin Radiol. 2009 Aug; 64(8): 792-800Zhang D, Hu LB, Zhen JW, Zou LG, Feng XY, Wang WX, Wen LAIM: To report the magnetic resonance imaging (MRI) features of intracranial cystic meningiomas and compare these features in intra- and peritumoural cyst groups. MATERIALS AND METHODS: Fourteen cases of peritumoural cystic meningiomas were compared with 18 cases of intratumoural cystic meningiomas. All